Fresh Frozen Plasma: Clinical Guidelines and Use

Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant.

The indications for transfusing fresh-frozen plasma (FFP), cryoprecipitate and cryosupernatant plasma are very limited. When transfused they can have unpredictable adverse effects. The risks of transmitting infection are similar to those of other blood components unless a pathogen-reduced plasma (PRP) is used. Of particular concern are allergic reactions and anaphylaxis, transfusion-related acu...

Prospective audit of the use of fresh-frozen plasma, based on Canadian Medical Association transfusion guidelines.

Appropriate and inappropriate use of fresh frozen plasma.

OBJECTIVE To analyze the current situation of use and misuse of fresh frozen plasma (FFP) in various clinical situations. METHODS This was a cross sectional study done at Liaquat National Hospital (LNH) during a period of 4 months from December 2002 to March 2003. About 300 file records of those patients who received fresh frozen plasma were studied. Each file record was checked for the diagn...

Fresh frozen plasma induced thrombocytopenia

Transfusions of blood products are common in medical practice and can be lifesaving in certain situations. Potentially life threatening reactions could occur and physicians should be alerted. Here we describe a case of thrombocytopenia that was induced by transfusion of fresh frozen plasma (FFP). A 52 years old male presented to the emergency department after two episodes of hematochezia that r...

Fresh-frozen plasma use in a South African tertiary hospital.

Despite available guidelines on indications for fresh-frozen plasma (FFP) transfusion, inappropriate use is increasing worldwide. We evaluated FFP administration to patients admitted to the Steve Biko Academic Hospital over 4 months, including indications for use and completeness of requisition forms. Transfusions were considered inappropriate for 39.5% of units administered. Of request forms s...